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Ortho-Core Adv. Multivitamin 180 caps

0.50 LBS
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Product Description


  • Supports overall health and well being
  • Contains superior forms of nutrients in efficient dosages
  • Provides balanced vitamins and minerals
  • Provides phytonutrients for extra health benefits
Ortho•Core is an advanced, balanced, and comprehensive multi-vitamin/mineral supplement. Ortho•Core contains a broad spectrum of vitamins, minerals, antioxidants and other factors for the maintenance of good health and to help the body metabolize carbohydrates, fats and proteins.

Supplement Facts
Serving Size: 6 Capsules
Vitamin A Complex    
   Retinol (Palmitate) 110 mcg RAE 363 IU
   Natural-Source Mixed Carotenoids:    
   - Beta-carotene 900 mcg RAE 1.8 mg
   - Lutein esters 6.8 mg  
   - Astaxanthin 2 mg  
   - Lycopene 5 mg  
 Vitamin B Complex    
    B1 (Thiamine) 9 mg  
    B2 (Riboflavin-5-phosphate) 2.5 mg  
    B3 (Niacin - from 126 mg inositol hexanicotinate) 115 mg  
    B5 (d-Ca Pantothenate) 100 mg  
    B6 (Pyridoxal-5'-phosphate) 100 mg  
    B12 (Methylcobalamin) 647 mcg  
    Folic Acid (calcium L-5-MTHF) 800 mcg  
    Biotin 300 mcg  
    Choline (bitartrate) 100 mg  
    Inositol (from inositol, inositol hexanicotinate†) 100 mg  
Vitamin C Complex (magnesium ascorbate) 120 mg  
Vitamin D3 (Cholecalciferol) 25 mcg  1000 IU
Vitamin E Complex    
   Mixed Tocopherols (soy, min. 65% gamma)  100 mg*  
   Vitamin E (from alpha-tocopherol) 7.1 mg ATE  10.6 IU
   Mixed Tocotrienols (palm) 10 mg**  
Vitamin K2 (MK-4, MK-7) 120 mcg  
Boron (citrate) 700 mcg  
Calcium (carbonate, citrate-malate) 300 mg  
Chromium (picolinate) 100 mcg  
Copper (citrate) 1.5 mg  
Iodine (Potassium iodide) 150 mcg  
Magnesium (aspartate, oxide, ascorbate) 210 mg  
Potassium (chloride) 50 mg  
Manganese (bisglycinate) 2.3 mg  
Molybdenum (Na Molybdate) 45 mcg  
Selenium (Selenomethionine) 55 mcg  
Silicon (HPV chelate) 25 mg  
Vanadium (citrate) 18 mcg  
Zinc (citrate) 11 mg  
Phytonutrients & Antioxidants    
Trans-Resveratrol 1.8 mg  
Grape Seed Extract (≥85% oligomeric proanthocyanidins) 100 mg  
R(α) Lipoic Acid (sodium salt)‡ 150 mg  
Co-enzyme Q10 (ubiquinone-10) 30 mg  
Green Tea Extract (≥45% EgCG, ≤1% caffeine) 140 mg  
N-acetylcysteine (NAC) 200 mg  
Quercetin 65 mg  
Mixed Citrus Bioflavonoids 25 mg  
†Total quantity of inositol hexanicotinate: 126 mg. *Tocopherols: >7.1 mg alpha, >1.3 mg beta, >64.8 mg gamma, >13.9 mg delta. **Tocotrienols: >2.8 mg alpha, 0.4 mg beta, >5.1 mg gamma, 1.4 mg delta. ‡Contains 15 mg sodium per serving. Non-medicinal ingredients: zeaxanthin, chlorophyllin copper complex, broccoli extract, microcrystalline cellulose, tocopherols, palm oil, starch (pea, rice, corn, soy), cellulose gum, acacia gum, sodium alginate, ascorbyl palmitate, sucrose, silicon dioxide, dicalcium and tricalcium phosphate, dextrin, maltodextrin, sorbitan stearate, hydroxypropyl cellulose. Capsule: hypromellose.
Store in tightly sealed container in a cool, dry place.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, peanuts, mustard or eggs.

Adult Dosage: Take up to 6 capsules daily with meals, or as directed by a qualified health care practitioner. Take a few hours before or after taking other medications.

Cautions: Consult a health care practitioner prior to use if you are taking blood thinners, blood pressure medication, antibiotics, nitroglycerin, or if you have diabetes, cystinuria, an iron deficiency or a liver disorder. Consult a health care practitioner if you develop symptoms of liver trouble (such as abdominal pain, dark urine or jaundice) or for use beyond 12 weeks. This product contains soy. Do not take if you have a soy allergy.

Pregnancy/Nursing: Do not take

Pharmaceutical synthesis; Natural botanical extracts; Tocopherols - soy; Tocotrienols - palm;

Main Indications:

  • General health

Deficiencies vs. Imbalances It has been well-established that the diet of mainstream society is rampantly deficient in essential nutrients. The need to redress these deficiencies has necessitated the existence of multivitamin formulations, and these formulations react to perceived deficiencies. If a study suggests we are not getting enough vitamin A, supplement manufacturers will often add an arbitrarily large amount of vitamin A to their multivitamin formulations. If another study emphasizes the importance of zinc, large amounts of zinc might be added in similar fashion. While this might make some short-term sense, it does not take into account that all nutrients work together and in synergy. For example, zinc depends on copper for optimum utilization, preferably in a 10 to 1 ratio. Therefore, any supplement manufacturer who adds more zinc to their multivitamin formulation will have to increase copper content proportionately. Failure to do so will result in an imbalance of this important ratio, leading to the suppression of copper-based antioxidant enzymes. Another example of these arbitrarily conceived amounts are the B-complex vitamins. One might be struck by the fact that multivitamins always seem to list their B-complex in precisely the same amounts. It is always the same 50 or 100 milligrams for each and every B vitamin (except for folic acid). What are the chances of the body optimally needing precisely the same amounts of half a dozen different B vitamins, each with its own exclusive biological role to play? Quality vs. Quantity The imbalance created by adding disproportionate amounts of certain nutrients is compounded by the fact that the composition of those nutrients is too often not of the optimal source. Therefore, excessive amounts of these synthetic and/or inferior nutrients can be at best wasteful, and at worst toxic or even harmful. Some studies have shown that extreme amounts of synthetic beta-carotene, for example, can lead to the body's carcinogen-detoxifying network becoming unbalanced, resulting (astonishingly) in the activation of genes related to the cancer process. So what is the answer to this random, arbitrary, ad-hoc approach to the formulation of daily multivitamins? The short answer is vigilance, especially from consumers, health professionals and supplement manufacturers. Vigilance in this case leads to a product called Ortho-Core. TM Enter the Core It was precisely the imbalances of this "mega-dose and hope for the best" archetype that led scientists at Advanced Orthomolecular Research® (AOR) to develop Ortho-Core. TM Ortho-CoreTM sets itself apart from other multivitamins in two ways: the first is that it does not concern itself with mega-doses. Instead, it pays extraordinary attention to balancing ratios of essential nutrients to one another in order to achieve a synergistic result. Secondly, it pays meticulous attention to combining diversely superior sources of those essential nutrients and balancing their ratios for optimal synergy as well. Here are some of the essential components of Ortho-CoreTM: Vitamin A Complex: Ortho-Core's vitamin A is a far cry from the mega-dose of beta-carotene found in some other "cutting edge" formulations. It contains the optimal dosage combined with an innovative diversity of carotenoids that includes alpha and beta carotene, lutein, zeaxanthin and lycopene. Even these diverse micronutrients are selected for an optimal ratio. Ortho-Core's full-spectrum vitamin A complex even encompasses an effective dose of astaxanthin, a unique carotenoid that even on its own has demonstrated effectiveness in clinical studies for eye, gastrointestinal and cardiovascular health. Vitamin B Complex: There is no 50 or 100 milligrams across the board here. The amount for each and every B vitamin is selected for the body's most efficient utilization. Furthermore, Ortho-CoreTM includes B-vitamins in their effective co-enzyme forms, including methylcobalamin and pyridoxal-5'-phosphate, the active co-enzyme forms of B-12 and B-6 respectively. Vitamin E Complex: Vitamin E is a complex that consists of eight different molecules. Most supplements contain only one vitamin E molecule: alpha-tocopherol, which actually lowers the levels of the other E molecules. The most common E molecule in food (and in Ortho-CoreTM), is gamma-tocopherol. New evidence suggests that gamma-tocopherol, far more than alpha-tocopherol, could yield remarkable results against cancer, heart disease, and Alzheimer's disease. Vitamin C Complex: Ortho-Core's vitamin C complex begins with a powerful dose of magnesium ascorbate, but it also contains a bioflavonoid mix that includes Quercetin. This ubiquitous micronutrient is known for preserving mitochondrial function in heart cells as well as inhibiting the androgen receptors involved in the development and progression of prostate cancer. Zinc-Copper Balance: Ortho-CoreTM includes a safe and optimal ratio of these two interdependent essential minerals. Trace Minerals: Official government nutrition panels only recognize 13 essential vitamins and 15 essential minerals. Recently, chromium was added to the latter, but the evidence is compelling that boron, silicon, and vanadium are just as necessary to maintain health, and Ortho-CoreTM includes them all. “Phytonutrients and Antioxidants: These include thousands of biologically active substances found in plants, and many have been shown to be protective, disease-preventing compounds. Ortho-CoreTM contains the phytonutrients most strongly supported by studied in humans, including grape seed extract, resveratrol and broccoli extract. Ortho Core also includes a series of diverse and effective compounds designed to enhance its already formidable nutrient arsenal. These include epigallocatechin gallate, or EgCG, the active ingredient in green tea which has anti-carcinogenic properties that are supported by extensive volumes of research. Also included are alpha-lipoic acid and Co-enzyme Q10. These enhancers of the mitochondria (the ‘powerhouse' of the cell) have long been part of the standard regimens of those truly determined to take charge of their own health. Alpha-lipoic acid and Co-enzyme Q10 also work synergistically with vitamins C and E, as well as n-acetylcysteine, or NAC, all of which are included in Ortho-Core.” Ortho-CoreTM was formulated to lead the pack, not follow it. Nor was it meant to rest on its laurels. This is reflected in the meticulous research involved from its inception to its manufacture - and its continuous improvement. The next time you make a choice in selecting your daily multivitamin, it would help to remember that a monsoon can be just as destructive as a drought, and that the latest forecast is always the most valuable. References Rygh O. Reserches sur les oligo elements. "I. Des l'importance du strontium, du baryum, du thallium et du zinc dans les scorbuts." Bull Soc Chim Biol. 1949;31:1052. Cited by (17, 19) Schroeder HA, Tipton IH, Nason AP. "Trace metals in man: strontium and barium." J Chronic Dis. 1972 Sep; 25(9):491-517 Paolini M, Antelli A, Pozzetti L, Spetlova D, Perocco P, Valgimigli L, Pedulli GF, Cantelli-Forti G. "Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats." Carcinogenesis. 2001 Sep; 22(9); 1483-95 Liu C, Wang XD, Bronson RT, Smith DE, Krinsky NI, Russell RM. "Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis. 2000 Dec;21(12): 2245-53 Stites TE, Rucker RB. "Physiological importance of quinoenzymes and the O-quinone family of cofactors.' J Nutr. 2000 Apr;130(4):719-27 Kasahara T, Kato T. Nutritional biochemistry: A new redox-cofactor vitamin for mammals. Nature. 2003. April 24;422(6934):832. Yuan H, Gong A, Young CY. "Involvement of transcription factor Sp1 in quercetin-mediated inhibitory effect on the androgen receptor in human prostate cancer cells." Carcinogenesis. 2005 Apr;26(4):793-801. Epub 2005 Jan 20. Sawaki K, et al. (2002) Sports performance benefits from taking natural astaxanthin characterized by visual activity and muscle improvements in humans. Journal of Clinical Therapeutics & Medicine 18(9): 73-88. Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer and optimizing health. Am J Clin Nutr. 2000 Jun; 71(6 Suppl): 1698S-702S. Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J. 1999 Feb;13(2):411-8. Baggio E, Gandini R, Plancher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. Mol Aspects Med. 1994; 15(Suppl):287-294.

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